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Common use

The main component of Silagra is Sildenafil.

Sildenafil affects the response to sexual stimulation. It acts by enhancing smooth muscle relaxation using nitric oxide, a chemical that is normally released in response to sexual stimulation. This smooth muscle relaxation allows increased blood flow into certain areas of the penis, which leads to an erection.

Sildenafil is applied for the treatment of erectile dysfunction (impotence) in men and pulmonary arterial hypertension.

Sildenafil may also be used for other purposes not listed above.

Dosage and direction

It is taken by mouth with a glass of water approximately 0,5-1 hour before sexual activity. Silagra should not be taken more than once a day.

A high fat meal may delay the time of the effect of this drug.

Try not to eat grapefruit or drink grapefruit juice while you are being treated with Sildenafil.


Before you start taking Sildenafil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.

Aged people may be more sensitive to the side effects of the drug.


Silagra is contraindicated in patients taking another medicine to treat impotence or using a nitrate drug for chest pain or heart problems.

This medicine should not be taken by women and children as well as in patients with a known hypersensitivity to any component of the tablet.

Possible side effect

The most common side effects are headache, flushing, heartburn, stomach upset, nasal stuffiness, lightheadedness, dizziness or diarrhea.

A serious allergic reaction to this drug is very rare, but seek immediate medical help if it occurs.

Many people using this medicine do not have serious side effects.

In case you notice any side effects not listed above, contact your doctor or pharmacist.

Drug interaction

This drug should not be used with nitrates and recreational drugs called "poppers" containing amyl or butyl nitrite; alpha-blocker medications; other medications for impotence; high blood pressure medicines, etc.

Consult your doctor or pharmacist for more details.

Missed dose

Silagra is used as needed, so you are unlikely to be on a dosing schedule.


If you think you have used too much of this medicine seek emergency medical attention right away. The symptoms of overdose usually include chest pain, nausea, irregular heartbeat, and feeling light-headed or fainting.


Store your medicines at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store the drugs in the bathroom. Keep all drugs away from reach of children and pets.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.


Other names used:

  • CialisĀ®

Active Ingredients:

  • Tadalafil

How does Tadalafil work and what pharmaceutical group does it belong to?

Tadalafil is a reversable selective inhibitor of the specific phosphodiesterase type 5(PDE5) cGMP. When sexual excitement causes local release of NO, inhibiting of PDE5 by Tadalafil causes an increase of cGMP levels in the cavernous body of the penis. This causes smooth muscles to relax and increases blood flow to the penis. Tadalafil does not cause an erection without sexual stimulation.

Tadalafil acts within 36 hours and effect occurs in 16 minutes after the sexual excitement. Tadalafil does not cause changes in systolic and diastolic pressure and heart rate.

Tadalafil is availabla in the form of soft tablets that are dissolved directly under the tongue. This increases the bioavalability of the preparation.

Which conditions are treated with Tadalafil?

Tadalafil is indicated for the treatment of erectile dysfunction.

What should a patient know prior taking the medication?

Tadalafil is contraindicated in patients with hypersensitivity to any of the medication ingredients.

Tadalafil is not approved to treat females or children and adolescents under 18 years of age.

Tadalafil should not be taken in patients which take organic nitrates.

Tadalafil should be used with caution in:

  • Cardiovascular disease including recent heart attacks, strokes, high or low blood pressure, heart failure, abnormal heart rhythm
  • Liver and kidney diseases
  • Vision problems
  • Blood diseases including Sickle cell anemia, leukemia
  • Penis deformation
  • Multiple myeloma

Which adverse effects may manifest when using the medication?

The most common Tadalafil side effects are associated with blocking of PDE5. These are: headache, stuffy nose, nasal congestion, dizziness, drowsiness, upset stomach or dyspepsia, hot flushing, pain in the arms, legs and muscles.

In rare cases Tadalafil may cause: angina, high blood pressure, insomnia, blurred vision, migraines, problems with vision and hearing.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Tadalafil?

The drug is affected by the following:

  • Alcoholic beverages
  • Alpha blockers
  • High blood pressure medicines
  • Antumycotics
  • Certain antibiotics
  • Grape fruit juice
  • Nitrates
  • Antivirals
  • Xantines(Theophylline)

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Tadalafil is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.